Description

4-Hydroxy-Dl-Tryptophan is a hydroxylated derivative of the essential amino acid tryptophan, serving as a key biochemical intermediate. This compound is valued for its role in the biosynthesis of serotonin and other bioactive indole alkaloids, making it a critical material for research and development. It is primarily utilized by the pharmaceutical, nutraceutical, and life science research industries for applications in metabolic studies, reference standards, and as a precursor for specialized synthesis.

Application

• Pharmaceutical Research & Development: As a biochemical precursor in the study of serotonin biosynthesis pathways and neurological research.
• Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, and other chromatographic methods for quality control and method validation.
• Nutraceutical Ingredient: Investigated for use in dietary supplements targeting mood and cognitive support due to its metabolic relationship to serotonin.
• Organic Synthesis: Serves as a versatile chiral building block for the synthesis of more complex indole-based compounds and fine chemicals.
• Biochemical Studies: Employed in enzymatic assays and metabolic pathway analysis to understand tryptophan metabolism.
• Academic & Institutional Research: A key reagent for universities and research institutes conducting studies in neurochemistry, pharmacology, and plant alkaloid biosynthesis.

Basic Information

Product Name	4-Hydroxy-Dl-Tryptophan
CAS No.	16533-77-0
Molecular Formula	C₁₁H₁₂N₂O₃
Molecular Weight	220.23 g/mol
Synonyms	DL-4-Hydroxytryptophan; 4-Hydroxy-DL-tryptophan; (±)-4-Hydroxytryptophan; 4-HTP (DL-form); 5-Hydroxy-DL-tryptophan isomer; α-Amino-1H-indole-4-propanoic acid; 3-(4-Hydroxy-1H-indol-3-yl)-DL-alanine; 4-Hydroxyindole-3-alanine
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-Dl-Tryptophan is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-grade specifications suitable for research and development. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.