Description

3,4-Dihydroxyhippuric Acid is a specialized phenolic acid derivative of significant interest in biochemical and pharmaceutical research. This compound serves as a key intermediate and reference standard in the study of metabolic pathways, particularly those involving tyrosine and polyphenol metabolism. It is primarily utilized by research institutions, pharmaceutical developers, and analytical laboratories focused on neuroscience, metabolic disorder research, and natural product analysis. Its defined structure makes it valuable for calibrating analytical methods and investigating bioactive compound mechanisms.

Application

• Biochemical Research Intermediate: Used as a precursor or metabolite analog in studies of catecholamine and polyphenol biosynthesis and degradation pathways.
• Pharmaceutical Reference Standard: Serves as a high-purity analytical standard for HPLC, LC-MS, or NMR in quality control and method development for related APIs.
• Neuroscience Research: Investigated for its potential role or as a biomarker in studies related to neurological function and disorders.
• Metabolic Pathway Analysis: Employed in in-vitro and in-vivo studies to trace and understand the metabolism of dietary polyphenols and related compounds.
• Enzyme Substrate or Inhibitor Studies: Used in enzymatic assays to study the activity of hydroxylases, transferases, or other relevant enzymes.
• Natural Product & Nutraceutical Research: Acts as a marker compound for the authentication and standardization of plant extracts and herbal products.

Basic Information

Product Name	3,4-Dihydroxyhippuric Acid
CAS No.	16533-60-1
Molecular Formula	C9H9NO5
Molecular Weight	211.17 g/mol
Synonyms	2-[(3,4-Dihydroxybenzoyl)amino]acetic acid; Hippuric acid, 3,4-dihydroxy-; N-(3,4-Dihydroxybenzoyl)glycine; 3,4-Dihydroxybenzoylglycine; DHHA; 3,4-DHHA
EINECS	Contact for details

Quality Control

Our 3,4-Dihydroxyhippuric Acid is produced under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques. A Certificate of Analysis (COA) detailing specific results for purity, related substances, and other critical parameters is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere. Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.