Description

D-6-Hydroxynorleucine is a non-proteinogenic amino acid derivative, serving as a key chiral building block and metabolic intermediate in advanced organic synthesis. Its value lies in providing a hydroxylated side chain for the construction of complex peptides, peptidomimetics, and active pharmaceutical ingredients (APIs). This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, including enzyme inhibitors and receptor modulators.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to incorporate a hydroxyl-functionalized norleucine analog, influencing peptide conformation and bioactivity.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and as a substrate for enzymatic transformations.
• Fine Chemical Synthesis: A versatile building block for creating specialized compounds in agrochemical and material science research.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	D-6-Hydroxynorleucine
CAS No.	16509-61-8
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	D-2-Amino-6-hydroxyhexanoic acid; (R)-2-Amino-6-hydroxycaproic acid; D-α-Amino-ε-hydroxycaproic acid; D-Hydroxynorleucine; (R)-6-Hydroxynorleucine; D-6-Hydroxy-2-aminocaproic acid; (2R)-2-Amino-6-hydroxyhexanoic acid; D-ε-Hydroxynorleucine
EINECS	Contact for details

Quality Control

Our D-6-Hydroxynorleucine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.