Description

Methyl 2,4-Dichloropyrimidine-6-Carboxylate is a high-purity, versatile pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional reactivity, featuring both a carboxylate ester and two chlorine substituents, makes it an essential intermediate for constructing complex heterocyclic systems. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with pyrimidine cores.
• Material Science Research: Used in the development of organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology: Serves as a scaffold for creating molecular probes and enzyme inhibitors in biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and process optimization.

Basic Information

Product Name	Methyl 2,4-Dichloropyrimidine-6-Carboxylate
CAS No.	16492-28-7
Molecular Formula	C6H4Cl2N2O2
Molecular Weight	207.01 g/mol
Synonyms	2,4-Dichloro-6-pyrimidinecarboxylic acid methyl ester; Methyl 2,4-dichloro-6-pyrimidinecarboxylate; 6-Methoxycarbonyl-2,4-dichloropyrimidine; 2,4-Dichloropyrimidine-6-carboxylic acid methyl ester; Methyl 2,4-dichloropyrimidine-6-carboxylate; 2,4-Dichloro-6-(methoxycarbonyl)pyrimidine; 2,4-Dichloro-6-carbomethoxypyrimidine
EINECS	Contact for details

Quality Control

Our Methyl 2,4-Dichloropyrimidine-6-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the stringent requirements for research and process chemistry. Certificates of Analysis (COA) with full batch traceability are provided and can be tailored to meet specific customer or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.