Description

2,4-Diaminopyrimidine-5-Carbonitrile is a high-value heterocyclic building block and key synthetic intermediate. This compound matters for its role as a versatile precursor in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing pyrimidine-based scaffolds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of kinase inhibitors, antiviral agents, and other bioactive molecules targeting pyrimidine-dependent pathways.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides that utilize diaminopyrimidine motifs.
• Chemical Research & Development: Serves as a versatile starting material for heterocyclic chemistry, enabling the construction of fused ring systems and complex molecular architectures.
• Material Science Precursor: Investigated for the development of organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional materials.

Basic Information

Product Name	2,4-Diaminopyrimidine-5-Carbonitrile
CAS No.	16462-27-4
Molecular Formula	C5H5N5
Molecular Weight	135.13 g/mol
Synonyms	5-Cyano-2,4-pyrimidinediamine; 2,4-Diamino-5-cyanopyrimidine; 5-Cyanopyrimidine-2,4-diamine; 2,4-Diamino-5-pyrimidinecarbonitrile; NSC 52378; AI3-52099; CCRIS 5981; 5-Pyrimidinecarbonitrile, 2,4-diamino-
EINECS	Contact for details

Quality Control

Our 2,4-Diaminopyrimidine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.