Description

5-Methylsulfonyl-1H-Pyrimidine-2,4-Dione is a high-purity, functionalized pyrimidine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable synthetic building block for the development of novel pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analogs and other active pharmaceutical ingredients (APIs) with potential antiviral or anticancer activity.
• Agrochemical Research: Used as a core scaffold for developing new herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probe: Employed in research to modify biomolecules or create activity-based probes for studying enzymatic processes.
• Material Science: Serves as a monomer or functional additive in the development of advanced polymers with specific electronic or photonic properties.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploration of new chemical spaces.

Basic Information

Product Name	5-Methylsulfonyl-1H-Pyrimidine-2,4-Dione
CAS No.	16417-11-1
Molecular Formula	C5H6N2O4S
Molecular Weight	190.18 g/mol
Synonyms	5-(Methylsulfonyl)pyrimidine-2,4(1H,3H)-dione; 5-Methanesulfonyluracil; 5-Methylsulfonyluracil; 2,4-Dihydroxy-5-methylsulfonylpyrimidine; 5-(Methylsulfonyl)-2,4(1H,3H)-pyrimidinedione; NSC 401005; 1H-Pyrimidine-2,4-dione, 5-(methylsulfonyl)-
EINECS	Contact for details

Quality Control

Our 5-Methylsulfonyl-1H-Pyrimidine-2,4-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.