Description

Glycodeoxycholic Acid Sodium Salt is a high-purity conjugated bile acid derivative, essential for critical biochemical and pharmaceutical research. Its primary value lies in its role as a key reference standard and biochemical tool for studying bile acid metabolism, membrane interactions, and receptor signaling pathways. This product is indispensable for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors, particularly those developing liver therapeutics, investigating cholestatic diseases, and formulating advanced drug delivery systems.

Application

• Pharmaceutical Reference Standard: Used as a certified primary standard for the quality control and assay of related drug substances and finished products.
• Biochemical Research: Serves as a critical reagent in studies of bile acid transporters (e.g., ASBT, NTCP), nuclear receptors (FXR, TGR5), and cholestasis mechanisms.
• Cell Culture & In-Vitro Diagnostics: Employed in cell-based assays and diagnostic kit development for liver function and metabolic disorders.
• Drug Formulation & Delivery: Investigated as an excipient or active component in formulations to enhance the solubility and bioavailability of poorly soluble drugs.
• Metabolite Analysis: Acts as a calibration standard in analytical techniques like LC-MS/MS and HPLC for quantifying bile acid profiles in biological samples.
• Enzymology Studies: Used as a substrate or inhibitor in enzymatic assays related to bile acid synthesis and conjugation pathways.

Basic Information

Product Name	Glycodeoxycholic Acid Sodium Salt
CAS No.	16409-34-0
Molecular Formula	C26H42NNaO5
Molecular Weight	471.61 g/mol
Synonyms	Sodium Glycodeoxycholate; Glycodeoxycholic Acid Sodium; N-[(3α,5β,12α)-3,12-Dihydroxy-24-oxocholan-24-yl]glycine Sodium Salt; Deoxycholylglycine Sodium Salt; GDCA-Na; GDC Sodium Salt; Sodium Glycochenodeoxycholate (isomer); 3α,12α-Dihydroxy-5β-cholan-24-oyl Glycine Sodium Salt
EINECS	240-417-2

Quality Control

Every batch of our Glycodeoxycholic Acid Sodium Salt is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for research and development. Comprehensive testing is performed, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Optical Rotation	Contact for details
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.