Description

H-Leu-Glu-Oh CAS NO 16364-31-1 is a high-purity dipeptide derivative, specifically the C-terminal free acid form of the leucine-glutamic acid sequence. This compound serves as a critical building block and intermediate in advanced peptide synthesis and biochemical research. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require high-quality, well-characterized peptide fragments for drug discovery, proteomics, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the solid-phase and solution-phase synthesis of longer, biologically active peptide chains for therapeutic development.
• Biochemical Research: Used as a standard or substrate in enzymatic studies, metabolic pathway analysis, and proteomics research.
• Peptide Library Construction: Essential component for creating combinatorial peptide libraries used in high-throughput screening for drug candidates.
• Nutraceutical & Cosmetic Peptide Synthesis: Intermediate in the production of bioactive peptides for functional food additives and advanced cosmetic actives.
• Academic & Institutional Research: Provides a defined, high-purity compound for university and institutional labs studying peptide structure, function, and interactions.

Basic Information

Product Name	H-Leu-Glu-Oh
CAS No.	16364-31-1
Molecular Formula	C11H20N2O5
Molecular Weight	260.29 g/mol
Synonyms	L-Leucyl-L-glutamic acid; Leu-Glu; H-Leu-Glu-OH; L-Leu-L-Glu; N-(L-Leucyl)-L-glutamic acid; (2S)-2-[[(2S)-2-Amino-4-methylpentanoyl]amino]pentanedioic acid; Leucine glutamic acid dipeptide; LG dipeptide
EINECS	Contact for details

Quality Control

Our H-Leu-Glu-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and residual solvent screening. We provide full traceability and documentation. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.