Description

5-Pyrimidinecarbonitrile, 4-Methoxy- (8Ci) is a versatile pyrimidine derivative, a key heterocyclic building block in advanced organic synthesis. Its molecular structure, featuring both a nitrile and a methoxy substituent, makes it a critical intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, leveraging the pyrimidine core for biological activity.
• Material Science Research: Acts as a building block for creating specialized organic ligands, dyes, or functional polymers with specific electronic properties.
• Academic & R&D Laboratories: Employed in methodological studies and as a standard reference compound in heterocyclic chemistry research.
• Chemical Library Development: A valuable component for constructing diverse compound libraries used in high-throughput screening for drug discovery.

Basic Information

Product Name	5-Pyrimidinecarbonitrile, 4-Methoxy- (8Ci)
CAS No.	16357-77-0
Molecular Formula	C6H5N3O
Molecular Weight	135.12 g/mol
Synonyms	4-Methoxypyrimidine-5-carbonitrile; 4-Methoxy-5-pyrimidinecarbonitrile; 5-Cyano-4-methoxypyrimidine; 4-Methoxy-5-cyanopyrimidine; 5-Pyrimidinecarbonitrile, 4-methoxy-; 4-Methoxypyrimidine-5-carbonitrile (8CI); 16357-77-0 (CAS)
EINECS	Contact for details

Quality Control

Our production of 5-Pyrimidinecarbonitrile, 4-Methoxy- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure consistency and meet the exacting standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.