Description

5-Pyrimidinecarbonitrile, 4-(Methylamino)- (8Ci,9Ci) is a specialized heterocyclic nitrile building block with significant synthetic utility. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel compounds with targeted biological activity. Its unique substitution pattern offers a strategic handle for further functionalization and ring system elaboration.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential kinase inhibitors, antiviral agents, and other small molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex heterocycles, dyes, and functional materials.
• Academic & Contract Research: Employed in medicinal chemistry programs and methodological studies for new C-N and C-C bond-forming reactions.
• Chemical Biology: Potential use in designing molecular probes and enzyme inhibitors for biochemical research.

Basic Information

Product Name	5-Pyrimidinecarbonitrile, 4-(Methylamino)- (8Ci,9Ci)
CAS No.	16357-70-3
Molecular Formula	C6H6N4
Molecular Weight	134.14 g/mol
Synonyms	4-(Methylamino)pyrimidine-5-carbonitrile; 4-Methylamino-5-cyanopyrimidine; 5-Cyano-4-(methylamino)pyrimidine; 4-(Methylamino)-5-pyrimidinecarbonitrile; 4-Methylaminopyrimidine-5-carbonitrile; 16357-70-3; 4-Methylamino-5-pyrimidinecarbonitrile
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarbonitrile, 4-(Methylamino)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.