Description

5-Pyrimidinecarbonitrile, 4-Chloro- (8Ci,9Ci) CAS NO 16357-68-9 is a high-purity, versatile heterocyclic building block characterized by its reactive chloro and cyano functional groups. This compound is essential for facilitating complex molecular synthesis, offering researchers and manufacturers a critical intermediate for constructing advanced chemical architectures. It is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, crop protection, and materials science.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and CNS-targeting drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyrimidine core contributes to biological activity.
• Organic Synthesis Building Block: Serves as a versatile precursor for further functionalization via nucleophilic substitution of the chloro group or modification of the cyano group.
• Material Science Research: Employed in the development of organic electronic materials, ligands for catalysis, and other functional organic compounds.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	5-Pyrimidinecarbonitrile, 4-Chloro- (8Ci,9Ci)
CAS No.	16357-68-9
Molecular Formula	C5H2ClN3
Molecular Weight	139.54 g/mol
Synonyms	4-Chloro-5-cyanopyrimidine; 4-Chloropyrimidine-5-carbonitrile; 5-Cyano-4-chloropyrimidine; 4-Chloro-5-pyrimidinecarbonitrile; 4-Chloro-5-pyrimidine nitrile; 16357-68-9; 4-Chloro-5-cyano-pyrimidine; 4-Chloro-pyrimidine-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarbonitrile, 4-Chloro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.