Description

4-Amino-3-Iodobenzotrifluoride is a versatile halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and iodine substituents on the aromatic ring make it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting receptor ligands and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or functionalization agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Chemical Research: Employed in academic and industrial R&D as a versatile scaffold for exploring new synthetic methodologies and creating compound libraries.
• Dye and Pigment Intermediate: Can be used in the synthesis of specialized dyes and pigments, leveraging the amino group for chromophore development.

Basic Information

Product Name	4-Amino-3-Iodobenzotrifluoride
CAS No.	16344-17-5
Molecular Formula	C7H5F3IN
Molecular Weight	287.02 g/mol
Synonyms	3-Iodo-4-aminobenzotrifluoride; 4-Amino-α,α,α-trifluoro-3-iodotoluene; 2-Iodo-α,α,α-trifluoro-p-toluidine; 1-Amino-2-iodo-4-(trifluoromethyl)benzene; 4-(Trifluoromethyl)-2-iodoaniline; 3-Iodo-4-(trifluoromethyl)aniline; Benzenamine, 3-iodo-4-(trifluoromethyl)-; 4-Amino-3-iodobenzotrifluoride
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Iodobenzotrifluoride is produced under a stringent quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request, providing full traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.