Description

L-Allylglycine is a non-proteinogenic amino acid derivative featuring an allyl side chain. This unique structure makes it a valuable chiral building block and a potent, irreversible inhibitor of the enzyme glutamate decarboxylase (GAD). It is essential for researchers and manufacturers in the pharmaceutical and life sciences sectors, particularly for neurological research, enzyme studies, and the synthesis of specialized bioactive compounds.

Application

• Pharmaceutical Intermediates: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Neurological Research: Used as a selective inhibitor of glutamate decarboxylase to study GABAergic systems, epilepsy, and related neurological pathways.
• Biochemical Research: Employed in enzymology studies to investigate the mechanism and kinetics of PLP-dependent decarboxylases.
• Peptide Synthesis: Incorporated into custom peptides to introduce the unique allylglycine moiety for structure-activity relationship (SAR) studies.
• Metabolite Analog: Acts as a mimic or antagonist in metabolic pathway analysis, particularly in amino acid metabolism.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	L-Allylglycine
CAS No.	16338-48-0
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
Synonyms	(S)-2-Amino-4-pentenoic Acid; (S)-2-Amino-4-pentenoic Acid; L-2-Amino-4-pentenoic Acid; (S)-Allylglycine; L-α-Amino-4-pentenoic Acid; S-Allylglycine; NSC 113986; GAD Inhibitor I
EINECS	Contact for details

Quality Control

Our L-Allylglycine is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.