Description

H-Abu-Gly-Oh is a protected dipeptide building block, specifically L-2-Aminobutyryl-glycine, widely used in solid-phase peptide synthesis (SPPS). This compound is essential for the controlled introduction of the non-proteinogenic amino acid 2-aminobutyric acid (Abu) into peptide sequences, enabling the creation of novel structures with tailored properties. It is a critical raw material for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Peptide Synthesis: A key intermediate for constructing peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in academic and industrial R&D for studying protein structure-function relationships and enzyme-substrate interactions.
• Combinatorial Chemistry: Serves as a versatile building block in libraries for high-throughput screening to discover new bioactive molecules.
• Proteomics & Diagnostics: Employed in the synthesis of labeled peptides and antigens for diagnostic assays and biomarker discovery.
• Cosmeceutical Peptides: A potential ingredient in the synthesis of advanced peptides for skincare and cosmetic applications.

Basic Information

Product Name	H-Abu-Gly-Oh
CAS No.	16305-80-9
Molecular Formula	C6H12N2O3
Molecular Weight	160.17 g/mol
Synonyms	L-2-Aminobutyryl-glycine; H-L-Abu-Gly-OH; (S)-2-Aminobutyrylglycine; Glycine, N-[(1S)-1-(aminomethyl)propyl]-; Abu-Gly; N-(2-Aminobutyryl)glycine; L-α-Aminobutyrylglycine; Peptide building block 16305-80-9
EINECS	Contact for details

Quality Control

Our H-Abu-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation by IR and NMR. Certificates of Analysis (COA) with detailed specifications are provided to ensure compliance with your research and cGMP-grade production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.