Description

Proline, 2-Methyl- (9Ci) is a non-proteinogenic amino acid derivative, specifically a methyl-substituted analog of L-proline. This compound is valued for its role as a specialized chiral building block and intermediate in advanced organic synthesis. It is primarily utilized by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and peptide chemistry. The material is supplied with a high level of purity and batch-to-batch consistency to meet stringent research and development requirements.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs) and prodrugs.
• Peptide Research: Used to incorporate modified proline residues into synthetic peptides to study structure-activity relationships and enhance metabolic stability.
• Agrochemical Synthesis: Acts as a building block for developing new herbicides, fungicides, and plant growth regulators with specific stereochemical requirements.
• Asymmetric Catalysis: Employed in the preparation of chiral ligands and organocatalysts for stereoselective chemical transformations.
• Biochemical Research: Utilized as a substrate or inhibitor in enzymatic studies to probe biological pathways involving proline metabolism.
• Fine Chemical Production: Functions as a specialized intermediate in the custom synthesis of complex organic molecules for various high-value applications.

Basic Information

Product Name	Proline, 2-Methyl- (9Ci)
CAS No.	16277-06-8
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
Synonyms	2-Methylproline; (2S)-2-Methylpyrrolidine-2-carboxylic acid; 2-Methyl-L-proline; 2-Methylproline, L-; 2-Methyl-2-pyrrolidinecarboxylic acid; α-Methylproline; 2-Pyrrolidinecarboxylic acid, 2-methyl-
EINECS	Contact for details

Quality Control

Our Proline, 2-Methyl- (9Ci) is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets high-purity standards suitable for research and synthesis. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profiles is available for every lot upon request, ensuring full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.