Description

L-Proline, 4-Amino-, cis- (9Ci) is a non-proteinogenic amino acid derivative, a stereospecific isomer of 4-aminoproline. This compound matters as a specialized chiral building block and intermediate for advanced organic synthesis and pharmaceutical research. It is needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel bioactive molecules and peptidomimetics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly those targeting collagen-related disorders or acting as enzyme inhibitors.
• Peptide Chemistry & Research: Used to incorporate constrained proline analogs into peptide sequences to study structure-activity relationships and enhance metabolic stability.
• Biochemical Research: Serves as a precursor or standard in studies of amino acid metabolism, collagen biosynthesis, and proline-specific enzymes.
• Agrochemical Synthesis: Employed as a building block for creating novel, biologically active compounds with potential herbicidal or fungicidal properties.
• Fine Chemical Production: Utilized in asymmetric synthesis and catalysis for the production of high-value, optically pure chemicals.

Basic Information

Product Name	L-Proline, 4-Amino-, cis- (9Ci)
CAS No.	16257-83-3
Molecular Formula	C₅H₁₀N₂O₂
Molecular Weight	130.15 g/mol
Synonyms	(2S,4S)-4-Aminopyrrolidine-2-carboxylic acid; cis-4-Amino-L-proline; (2S,4S)-4-Aminoproline; L-cis-4-Hydroxyproline, 4-amino-; 4-Aminoproline; 4-Amino-L-proline (cis); 4-Azaproline; 4-NH2-Pro
EINECS	Contact for details

Quality Control

Our L-Proline, 4-Amino-, cis- (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing purity, identity, and specific test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent absorption of water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (cis isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.