Description

Bombesin 13-14 is a specific bioactive peptide fragment derived from the full bombesin sequence. This compound is a critical research-grade biochemical tool used extensively in neuroscience and endocrinology studies. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focusing on receptor-ligand interactions and signal transduction pathways.

Application

• Neuroscience Research: Used as a specific ligand to study the binding and function of bombesin receptor subtypes (BB1, BB2, BB3) in the central and peripheral nervous systems.
• Endocrinology Studies: Employed in research investigating the role of bombesin-like peptides in regulating gastrointestinal hormone secretion and satiety signals.
• Cancer Research: Utilized in vitro and in vivo studies to explore the overexpression of bombesin receptors in certain cancers, such as small cell lung carcinoma and prostate cancer.
• Biochemical Assay Development: Serves as a standard or reference compound in the development and validation of immunoassays (ELISA, RIA) and receptor binding assays.
• Cell Signaling Pathway Analysis: Applied in studies to map intracellular signaling cascades (e.g., calcium mobilization, MAPK activation) initiated by bombesin receptor activation.
• Pharmacology & Drug Discovery: Acts as a key tool compound for screening and characterizing novel bombesin receptor agonists or antagonists for therapeutic potential.

Basic Information

Product Name	Bombesin 13-14
CAS No.	16217-56-4
Molecular Formula	C14H22N4O4
Molecular Weight	310.35 g/mol
Synonyms	Bombesin (13-14); L-Glutaminyl-L-tryptophan; Gln-Trp; Pyr-Gln-Trp; Pyr-Gln-Trp-NH2; Pyr-Q-W-NH2; Bombesin C-terminal dipeptide; 5-Oxo-L-prolyl-L-glutaminyl-L-tryptophanamide
EINECS	Contact for details

Quality Control

Our Bombesin 13-14 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements of research applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), identity confirmation (by MS and NMR), and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.