Description

n-Benzyloxycarbonylphenylalanylalanine is a protected dipeptide building block of significant importance in synthetic organic and medicinal chemistry. Its primary value lies in its role as a key intermediate for the controlled synthesis of more complex peptides and peptidomimetics, where the benzyloxycarbonyl (Cbz) group provides orthogonal protection for the amine functionality. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing novel therapeutic agents, enzyme inhibitors, or conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Critical building block for the solid-phase and solution-phase synthesis of bioactive peptides and potential drug candidates.
• Peptidomimetic Research: Used in the design and construction of peptidomimetics, which are molecules that mimic peptides but with enhanced metabolic stability and bioavailability.
• Protease Inhibitor Development: Serves as a core structure or precursor in the synthesis of inhibitors for various proteolytic enzymes.
• Bioconjugation: Can be utilized in the preparation of peptide conjugates for diagnostic or targeted drug delivery applications.
• Chemical Biology Probes: Employed in the synthesis of labeled or modified peptides used as tools to study biological processes and protein interactions.
• Academic & R&D: A valuable reagent for university and institutional research laboratories focused on organic synthesis methodology and peptide chemistry.

Basic Information

Product Name	n-Benzyloxycarbonylphenylalanylalanine
CAS No.	16088-00-9
Molecular Formula	C20H22N2O5
Molecular Weight	370.40 g/mol
Synonyms	Z-Phe-Ala-OH; Cbz-Phe-Ala-OH; N-Carbobenzoxy-L-phenylalanyl-L-alanine; Nα-Cbz-L-phenylalanyl-L-alanine; Benzyloxycarbonyl-L-phenylalanyl-L-alanine; (2S)-2-[[(2S)-2-(benzyloxycarbonylamino)-3-phenylpropanoyl]amino]propanoic acid; N-Benzyloxycarbonyl-L-phenylalanyl-L-alanine; Z-L-Phe-L-Ala-OH
EINECS	Contact for details

Quality Control

Our n-Benzyloxycarbonylphenylalanylalanine is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity for research and cGMP manufacturing applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support regulatory filings with appropriate documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.