Description

L-Kynurenine Sulfate is a high-purity, crystalline salt form of the essential amino acid metabolite L-Kynurenine. This compound serves as a critical biochemical precursor and research tool in the study of tryptophan metabolism and neuroactive pathways. It is primarily utilized by research institutions and pharmaceutical developers focused on neuroscience, immunology, and metabolic disease. The product, identified as CAS NO 16055-80-4, is supplied to meet the stringent requirements of advanced life science applications.

Application

• Biochemical Research: Essential standard and precursor for studying the kynurenine pathway in tryptophan metabolism.
• Neuroscience & Neuropharmacology: Investigated for its role as a precursor to neuroactive agents like quinolinic acid and kynurenic acid, relevant to neurodegenerative conditions.
• Immunology Research: Used in studies exploring immunomodulation, as kynurenine pathway metabolites influence T-cell regulation and immune tolerance.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in drug discovery.
• Cell Culture & In Vitro Studies: Employed in media supplementation to modulate cellular metabolic pathways in experimental models.
• Enzymology: Substrate for enzymes such as kynureninase and kynurenine aminotransferase in kinetic and inhibitory assays.

Basic Information

Product Name	L-Kynurenine Sulfate
CAS No.	16055-80-4
Molecular Formula	C10H12N2O4 • H2SO4
Molecular Weight	304.28 g/mol (free base: 208.21)
Synonyms	L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid sulfate; (S)-Kynurenine sulfate; Kynurenine L-form sulfate; Kynurenine acid sulfate; Kynurenine sulfate salt; L-Kynurenine hydrogen sulfate; H-Kyn-OH sulfate
EINECS	Contact for details

Quality Control

Our L-Kynurenine Sulfate is manufactured under controlled conditions to ensure high chemical and isomeric purity suitable for research applications. Each batch undergoes rigorous analytical testing, including HPLC for assay and chiral purity, to confirm identity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent absorption of atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% L-Isomer
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Sulfate Content	Conforms to theoretical
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.