Description

L-Kynurenine Sulfate is a high-purity, crystalline salt form of the essential tryptophan metabolite L-Kynurenine. This compound is a critical biochemical intermediate in the kynurenine pathway, which plays a pivotal role in immune regulation and neurological function. It is primarily utilized by research institutions and pharmaceutical developers focused on neurobiology, immunology, and metabolic disease research. The sulfate salt form offers enhanced stability and solubility for precise experimental and formulation work.

Application

• Biochemical Research: A key standard and reagent for studying the kynurenine pathway, neuroinflammation, and neurodegenerative mechanisms.
• Pharmaceutical Development: Serves as a critical reference compound and potential intermediate in the development of therapies targeting neurological disorders, immune modulation, and cancer.
• Cell Culture & In Vitro Studies: Used to modulate cellular pathways in immunological and neurological cell-based assay systems.
• Diagnostic Reagent Manufacturing: Employed in the production of calibrators and controls for diagnostic kits measuring tryptophan metabolism markers.
• Metabolomics & Analytical Standards: A high-purity certified reference material for quantitative analysis in LC-MS, HPLC, and other analytical platforms.
• Enzymology Studies: Substrate for enzymes like kynurenine 3-monooxygenase (KMO) and kynureninase in enzymatic activity assays.

Basic Information

Product Name	L-Kynurenine Sulfate
CAS No.	16055-30-4
Molecular Formula	C10H12N2O4 • H2SO4
Molecular Weight	304.29 g/mol (free base: 208.21)
Synonyms	L-Kynurenine Sulfate Salt; (S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid sulfate; Kynurenine Sulfate; H-Kyn-OH • H2SO4; L-2-Amino-4-(2-aminobenzoyl)butyric acid sulfate; (S)-Kynurenine Sulfate; Kynurenine, L-, sulfate (1:1)
EINECS	Contact for details

Quality Control

Our L-Kynurenine Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity verification, and identity confirmation by IR and NMR. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards. We support custom purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to prevent degradation from moisture absorption and light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.