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2(1H)-Pyrimidinone, 4-Amino-1-α-L-Arabinofuranosyl- CAS NO 16033-23-1


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CAS No.:16033-23-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2(1H)-Pyrimidinone, 4-Amino-1-α-L-Arabinofuranosyl- is a nucleoside analog with significant biochemical and pharmaceutical relevance. This compound is valued for its role as a key intermediate and building block in the synthesis of antiviral and anticancer agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of nucleoside-based therapeutics and molecular biology research.

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of antiviral and anticancer nucleoside drugs.
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and metabolic pathway research.
  • Antiviral Agent Development: Serves as a core scaffold for developing novel therapeutics targeting viral polymerases.
  • Molecular Biology: Employed in the study of nucleic acid chemistry and the design of modified oligonucleotides.
  • Academic & Industrial R&D: Fundamental building block for medicinal chemistry programs and high-throughput screening libraries.

Basic Information

Product Name 2(1H)-Pyrimidinone, 4-Amino-1-α-L-Arabinofuranosyl-
CAS No. 16033-23-1
Molecular Formula C9H13N3O5
Molecular Weight 243.22 g/mol
Synonyms 4-Amino-1-β-L-arabinofuranosyl-2(1H)-pyrimidinone; 1-β-L-Arabinofuranosylcytosine; β-L-Arabinofuranosylcytosine; L-Arabinofuranosylcytosine; L-Ara-C; L-Cytosine arabinoside; L-Arabinosylcytosine; 4-Amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
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Quality Control

Our 2(1H)-Pyrimidinone, 4-Amino-1-α-L-Arabinofuranosyl- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference standard
Assay (HPLC) ≥98.0%
Water Content (KF) ≤1.0%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm
Related Substances (HPLC) Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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