Description

2-Amino-3-(5-Iodo-1H-Indol-3-Yl)Propanoic Acid is a halogenated derivative of the essential amino acid tryptophan, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel pharmaceuticals and bioactive molecules, particularly those targeting neurological pathways. Researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors need this high-purity intermediate for drug discovery programs and the synthesis of complex peptidomimetics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those with indole-based structures for central nervous system (CNS) targets.
• Biochemical Research: Used as a specialized reagent in proteomics and metabolic pathway studies to investigate tryptophan metabolism and iodinated protein interactions.
• Peptide Synthesis: Incorporation into custom peptides and peptidomimetics to introduce iodine labels or modify biological activity and receptor binding.
• Radiopharmaceutical Development: Serves as a starting material for developing iodine-123 or iodine-131 labeled compounds for diagnostic imaging or therapy.
• Agrochemical Research: Intermediate in the discovery of new plant growth regulators or herbicides with specific mode-of-action.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2-Amino-3-(5-Iodo-1H-Indol-3-Yl)Propanoic Acid
CAS No.	15641-49-3
Molecular Formula	C11H11IN2O2
Molecular Weight	330.12 g/mol
Synonyms	5-Iodo-DL-tryptophan; 5-Iodotryptophan; DL-5-Iodotryptophan; (RS)-2-Amino-3-(5-iodo-1H-indol-3-yl)propanoic acid; 2-Azaniumyl-3-(5-iodo-1H-indol-3-yl)propanoate; 5-Iodo-Trp; 5-I-DL-Trp; α-Amino-1H-indole-3-propanoic acid, 5-iodo-
EINECS	Contact for details

Quality Control

Our 2-Amino-3-(5-Iodo-1H-Indol-3-Yl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting purity, related substances, and other critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.