Description

L-Threo-Dihydrosphingosine is a high-purity, stereochemically defined sphingolipid backbone essential for advanced biochemical research and synthesis. This compound serves as a critical intermediate in the study of cellular signaling pathways, membrane biology, and the development of novel therapeutics. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications ranging from lipidomics to drug discovery.

Application

• Biochemical Research: A fundamental building block for studying sphingolipid metabolism, ceramide synthesis, and cell signaling cascades.
• Pharmaceutical Intermediates: Serves as a key chiral synthon in the production of sphingolipid-based drug candidates and active pharmaceutical ingredients (APIs).
• Lipidomics Standards: Used as a certified reference standard in mass spectrometry for the accurate quantification and profiling of sphingolipids in biological samples.
• Cell Culture & Neuroscience: Employed in studies of neuronal development, apoptosis, and membrane dynamics in specialized cell culture systems.
• Cosmeceutical R&D: Investigated for its potential role in skin barrier function and the development of advanced dermatological formulations.

Basic Information

Product Name	L-Threo-Dihydrosphingosine
CAS No.	15639-50-6
Molecular Formula	C18H39NO2
Molecular Weight	301.51 g/mol
Synonyms	(2S,3R)-2-Amino-1,3-octadecanediol; D-erythro-Sphinganine; (2S,3R)-2-Aminooctadecane-1,3-diol; Sphinganine; Dihydro-D-erythro-sphingosine; L-Threo-D-erythro-Dihydrosphingosine; 15639-50-6
EINECS	Contact for details

Quality Control

Our L-Threo-Dihydrosphingosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identity confirmation via IR and MS. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (L-Threo isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.