Description

5-Methyl-5,6-Dihydropteroylglutamic Acid is a key folate derivative and intermediate in biochemical pathways, offering significant value for research and synthesis. This compound is essential for developing analytical standards, reference materials, and investigating metabolic processes related to vitamin B9. It is primarily sought by manufacturers and research institutions in the pharmaceutical, nutraceutical, and life science research sectors.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of specialized folate analogs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies and metabolic pathway analysis.
• Nutraceutical Development: Serves as a precursor in the formulation of advanced folate-based nutritional supplements.
• Analytical Chemistry: Employed as a high-purity standard for HPLC, LC-MS, and other analytical method development and validation.
• Enzyme Inhibition Studies: Utilized in research targeting dihydrofolate reductase (DHFR) and related enzymes.

Basic Information

Product Name	5-Methyl-5,6-Dihydropteroylglutamic Acid
CAS No.	15623-13-9
Molecular Formula	C20H23N7O6
Molecular Weight	457.44 g/mol
Synonyms	5-Methyl-5,6-dihydrofolic acid; 5-Methyl-DHFA; 5-Methyl-5,6-dihydropteroyl-L-glutamic acid; 5-CH3-H4PteGlu; NSC 139490; 5-Methyltetrahydrofolate precursor; 5-Methyl-5,6,7,8-tetrahydrofolic acid (common name reference)
EINECS	Contact for details

Quality Control

Our 5-Methyl-5,6-Dihydropteroylglutamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere for long-term stability and to minimize degradation.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.