Description

2-Amino-4,6-dichloro-5-fluoropyrimidine is a high-value halogenated pyrimidine building block essential for advanced organic synthesis. This compound matters because its unique substitution pattern makes it a critical intermediate for constructing complex molecules with specific biological activities. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated nucleoside analogs and other potential therapeutic agents.
• Agrochemical Development: Used in research to create novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Research: Serves as a versatile building block for heterocyclic chemistry and medicinal chemistry programs.
• Material Science: Potential precursor for the development of specialty polymers and advanced organic electronic materials.
• Contract Manufacturing: Supplied to CDMOs for custom synthesis and scale-up projects requiring fluoropyrimidine chemistry.

Basic Information

Product Name	2-Amino-4,6-dichloro-5-fluoropyrimidine
CAS No.	15598-33-1
Molecular Formula	C4H2Cl2FN3
Molecular Weight	181.98 g/mol
Synonyms	5-Fluoro-2-amino-4,6-dichloropyrimidine; 4,6-Dichloro-5-fluoro-2-pyrimidinamine; 2-Pyrimidinamine, 4,6-dichloro-5-fluoro-; 5-Fluoro-4,6-dichloropyrimidin-2-amine; ADFP; NSC 403914
EINECS	Contact for details

Quality Control

Our 2-Amino-4,6-dichloro-5-fluoropyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The product is moisture-sensitive; ensure containers are sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.