Description

Ac-Ala-Ala-Ala-Ala-Oh is a synthetic tetrapeptide derivative featuring an acetylated N-terminus and a free C-terminal carboxylic acid. This compound serves as a crucial building block and model substrate in peptide chemistry and biochemical research. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications ranging from enzyme studies to the development of novel therapeutic agents.

Application

• Enzyme Substrate & Inhibitor Studies: Used as a model substrate for investigating the specificity and kinetics of proteolytic enzymes like elastase and other serine proteases.
• Peptide Synthesis Intermediate: Acts as a key fragment or starting material in the solid-phase or solution-phase synthesis of longer, more complex peptide sequences.
• Biochemical Research: Employed in studies of peptide structure, folding, stability, and interactions due to its well-defined alanine-based sequence.
• Pharmaceutical Development: Utilized in early-stage research for screening and developing peptide-based drugs targeting various diseases.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in peptide analysis (HPLC, MS).
• Material Science: Investigated for the creation of bio-inspired materials and self-assembling peptide nanostructures.

Basic Information

Product Name	Ac-Ala-Ala-Ala-Ala-Oh
CAS No.	15483-58-6
Molecular Formula	C16H26N4O6
Molecular Weight	370.40 g/mol
Synonyms	Ac-AAAA-OH; Acetyl-tetraalanine; N-Acetyl-L-alanyl-L-alanyl-L-alanyl-L-alanine; N-Acetyl-Ala-Ala-Ala-Ala; Ac-Ala4-OH; Acetyl Ala-Ala-Ala-Ala; Tetrapeptide AAAA acetate; N-Acetyl tetraalanine
EINECS	Contact for details

Quality Control

Our Ac-Ala-Ala-Ala-Ala-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure enantiomeric purity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with research and development grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be kept under dry, inert conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.