Description

(3R)-3,4,5,6-Tetrahydro-4β,5β-Dihydroxy-3β,6β-Epoxy-2H,8H-Pyrimido[6,1-B][1,3]Oxazocine-8,10(9H)-Dione is a complex heterocyclic compound with a fused pyrimido-oxazocine structure, serving as a sophisticated chemical building block. Its unique stereochemistry and functional groups make it a valuable intermediate for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs). This high-purity compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new molecules with specific biological activities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel drug candidates, particularly for complex target molecules.
• Agrochemical Research: Used as a precursor in developing new pesticides or herbicides with specific modes of action.
• Fine Chemical Synthesis: Serves as a building block for creating specialized ligands, catalysts, or advanced materials.
• Academic & Contract Research: A valuable tool for methodological studies in organic chemistry, asymmetric synthesis, and heterocyclic chemistry.
• Bioconjugate Chemistry: Potential use in designing linkers or payloads for antibody-drug conjugates (ADCs) due to its functionalizable scaffold.

Basic Information

Product Name	(3R)-3,4,5,6-Tetrahydro-4β,5β-Dihydroxy-3β,6β-Epoxy-2H,8H-Pyrimido[6,1-B][1,3]Oxazocine-8,10(9H)-Dione
CAS No.	15425-10-2
Molecular Formula	C10H10N2O6
Molecular Weight	254.20 g/mol
Synonyms	Pyrimido[6,1-b][1,3]oxazocine-8,10(9H)-dione, 3,4,5,6-tetrahydro-4b,5b-dihydroxy-3b,6b-epoxy-, (3R)-; 15425-10-2; (3R)-rel-(3aR,4aS,6aS,6bR)-Tetrahydro-4a,5-dihydroxy-3a,6a-epoxyfuro[3',4':4,5]pyrimido[1,6-b][1,3]oxazine-8,10(3H,9H)-dione; Uracil spirooxirane derivative
EINECS	Contact for details

Quality Control

Every batch of (3R)-3,4,5,6-Tetrahydro-4β,5β-Dihydroxy-3β,6β-Epoxy-2H,8H-Pyrimido[6,1-B][1,3]Oxazocine-8,10(9H)-Dione is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and chiral analysis, to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are available upon request. We support development projects with custom purity grades and analytical method development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.