Description

β-Methoxy-3-(Trifluoromethyl)Phenethylamine is a specialized fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the electron-donating methoxy group and the strongly electron-withdrawing trifluoromethyl group on the phenethylamine scaffold, enabling precise modulation of physicochemical properties in target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, particularly where enhanced metabolic stability, bioavailability, or specific receptor binding is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially for central nervous system (CNS) targets, antidepressants, and psychoactive substances.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and insecticides that leverage the stability imparted by the trifluoromethyl group.
• Ligand & Catalyst Development: Used to create specialized ligands for asymmetric catalysis or metal-organic frameworks (MOFs).
• Fluorinated Compound Library Synthesis: Essential for medicinal chemistry programs focused on expanding fluorinated chemical space for high-throughput screening.
• Biochemical Probe Synthesis: Serves as a starting material for creating labeled compounds or probes used in biochemical and pharmacological studies.
• Material Science Precursor: Potential monomer or intermediate for synthesizing advanced polymers with specific optical or electronic properties.

Basic Information

Product Name	β-Methoxy-3-(Trifluoromethyl)Phenethylamine
CAS No.	15235-08-2
Molecular Formula	C10H12F3NO
Molecular Weight	219.20 g/mol
Synonyms	2-(3-Methoxy-α-methylbenzyl)-1,1,1-trifluoroethaneamine; 1-(3-Methoxyphenyl)-2-(trifluoromethyl)ethylamine; 2-Methoxy-α-(trifluoromethyl)phenethylamine; 3-Methoxy-α-(trifluoromethyl)benzeneethanamine; β-Methoxy-α-(trifluoromethyl)phenethylamine; 1-[3-Methoxyphenyl]-2,2,2-trifluoroethanamine; 2,2,2-Trifluoro-1-(3-methoxyphenyl)ethanamine
EINECS	Contact for details

Quality Control

Our β-Methoxy-3-(Trifluoromethyl)Phenethylamine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.