Description

Ethyl 6-(Bromomethyl)-2-Oxo-4-Thien-2-Yl-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is a high-value brominated tetrahydropyrimidine derivative, serving as a critical pharmaceutical intermediate and synthetic building block for advanced organic synthesis. Its unique molecular structure, featuring both a reactive bromomethyl group and a tetrahydropyrimidine core, makes it indispensable for constructing complex heterocyclic compounds. This compound is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitutions to introduce functionalized tetrahydropyrimidine moieties.
• Agrochemical Research: Intermediate for developing new generation pesticides and herbicides with novel modes of action.
• Material Science: Used in the research and development of specialty polymers and advanced organic materials.
• Academic & Contract Research: Serves as a valuable reagent for methodological studies and library synthesis in academic and industrial research laboratories.

Basic Information

Product Name	Ethyl 6-(Bromomethyl)-2-Oxo-4-Thien-2-Yl-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
CAS No.	15139-62-5
Molecular Formula	C₁₂H₁₃BrN₂O₃S
Molecular Weight	345.21 g/mol
Synonyms	Ethyl 6-(bromomethyl)-2-oxo-4-(thiophen-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 5-Carboxyethyl-6-bromomethyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydropyrimidine; 4-(2-Thienyl)-6-(bromomethyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic Acid Ethyl Ester; 6-Bromomethyl-4-(2-thienyl)-1,2,3,4-tetrahydro-2-oxopyrimidine-5-carboxylic Acid Ethyl Ester; DHPM-Br derivative
EINECS	Contact for details

Quality Control

Our Ethyl 6-(Bromomethyl)-2-Oxo-4-Thien-2-Yl-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistent performance as a synthesis intermediate. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged procedures to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.