Description

Cyclo(L-Leucyl-L-Tryptophyl) CAS NO 15136-34-2 is a synthetic cyclic dipeptide, also known as a diketopiperazine (DKP), composed of the amino acids L-leucine and L-tryptophan. This compound is of significant interest in pharmaceutical research and development due to its potential as a bioactive scaffold and its role in peptide chemistry. It serves as a critical intermediate or reference standard for researchers in medicinal chemistry, biochemistry, and process development. Industries requiring high-purity, well-characterized peptide derivatives for drug discovery and analytical applications are the primary users of this material.

Application

• Pharmaceutical Intermediate: Used as a key building block or precursor in the synthesis of more complex peptide-based drugs and bioactive molecules.
• Medicinal Chemistry Research: Serves as a core scaffold for studying structure-activity relationships (SAR) and developing new therapeutic agents.
• Biochemical Research: Employed in studies of enzyme inhibition, receptor binding, and other biological pathways where cyclic dipeptides play a role.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in HPLC, LC-MS, and other analytical techniques.
• Process Development & Scale-up: Utilized in optimizing synthetic routes and manufacturing processes for peptide APIs (Active Pharmaceutical Ingredients).
• Cosmetic & Personal Care Actives: Investigated for potential use in advanced skincare formulations due to the bioactive properties of peptide derivatives.

Basic Information

Product Name	Cyclo(L-Leucyl-L-Tryptophyl)
CAS No.	15136-34-2
Molecular Formula	C17H21N3O2
Molecular Weight	299.37 g/mol
Synonyms	Cyclo(Leu-Trp); Cyclo(L-Leu-L-Trp); L-Leucyl-L-tryptophan anhydride; 3-Benzyl-6-isobutyl-2,5-piperazinedione; 2,5-Piperazinedione, 3-benzyl-6-(2-methylpropyl)-, (3S,6S)-; Diketopiperazine (Leu-Trp); c(Leu-Trp); (3S,6S)-3-Benzyl-6-isobutylpiperazine-2,5-dione
EINECS	Contact for details

Quality Control

Our Cyclo(L-Leucyl-L-Tryptophyl) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We can supply material compliant with various pharmacopeial standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.