Description

Carbobenzyloxyglycylglycyl-L-Tyrosine Benzyl Ester is a protected tripeptide derivative, specifically a Cbz-Gly-Gly-Tyr-OBzl building block, essential for advanced peptide synthesis. This compound is a critical intermediate for researchers and manufacturers developing complex peptides for pharmaceutical and biochemical applications. It is primarily utilized in solid-phase and solution-phase peptide synthesis (SPPS) to construct larger, biologically active peptide sequences, serving the needs of the pharmaceutical R&D, biotechnology, and academic research sectors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of therapeutic peptides and peptidomimetics.
• Solid-Phase Peptide Synthesis (SPPS): Used as a protected amino acid sequence to elongate peptide chains on resin.
• Solution-Phase Peptide Synthesis: Employed in classical coupling strategies for constructing specific peptide fragments.
• Biochemical Research: Serves as a substrate or intermediate in enzymatic studies and proteomics research.
• API Development: Integral to the research and development process for new Active Pharmaceutical Ingredients (APIs) with tyrosine-containing sequences.
• Custom Peptide Service: A fundamental reagent for CROs (Contract Research Organizations) and CDMOs (Contract Development and Manufacturing Organizations) offering bespoke peptide production.

Basic Information

Product Name	Carbobenzyloxyglycylglycyl-L-Tyrosine Benzyl Ester
CAS No.	15115-03-4
Molecular Formula	C27H27N3O7
Molecular Weight	505.52 g/mol
Synonyms	Cbz-Gly-Gly-Tyr-OBzl; Z-Gly-Gly-Tyr-OBzl; N-Carbobenzyloxy-glycyl-glycyl-L-tyrosine benzyl ester; Benzyl N-[(benzyloxy)carbonyl]glycylglycyl-L-tyrosinate; Z-Gly-Gly-Tyr-OBzl; CBZ-Gly-Gly-Tyr-OBzl; (Benzyloxy)carbonyl-Gly-Gly-Tyr-OBzl; Nα-Carbobenzyloxy-glycyl-glycyl-L-tyrosine benzyl ester
EINECS	Contact for details

Quality Control

Our Carbobenzyloxyglycylglycyl-L-Tyrosine Benzyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.