Description

3-Stearoyl-Sn-Glycerol is a structured monoglyceride, specifically the 1-monostearin isomer, where a stearic acid moiety is esterified to the *sn*-3 position of the glycerol backbone. This precise molecular configuration is critical for applications requiring specific lipid digestion, absorption, and crystallization behavior. It serves as a high-purity synthetic intermediate and a functional lipid component for advanced research and product development. Key industries that utilize this compound include pharmaceuticals, nutraceuticals, and specialty chemical synthesis.

Application

• Pharmaceutical Excipient: Used as a lipid-based carrier in solid dosage forms and as a component in self-emulsifying drug delivery systems (SEDDS) to enhance the bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs).
• Nutraceutical & Food Science: Acts as a structuring agent in lipid gels (oleogels) for fat replacement strategies and as a model compound for studying fat metabolism and the synthesis of structured triglycerides.
• Biochemical Research: Serves as a standard and substrate in enzymatic studies, particularly for lipases and phospholipases, to investigate reaction specificity and kinetics.
• Cosmetic Formulations: Employed as an emollient and texture modifier in creams and ointments, providing stability and a desirable sensory profile.
• Chemical Synthesis: A key chiral building block for the synthesis of more complex glycerolipids, phospholipids, and other bioactive molecules.

Basic Information

Product Name	3-Stearoyl-Sn-Glycerol
CAS No.	14811-92-8
Molecular Formula	C21H42O4
Molecular Weight	358.56 g/mol
Synonyms	1-Monostearin; 1-Monostearoylglycerol; 1-Glyceryl stearate; 1-Stearoylglycerol; 3-Monostearoylglycerol; (R)-1-Stearoyl-glycerol; α-Monostearin; Glycerol 1-stearate
EINECS	Contact for details

Quality Control

Our 3-Stearoyl-Sn-Glycerol is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA). Specifications can be aligned with research-grade or pharmaceutical excipient standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or flakes
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	70 - 75 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.