Description

Ethyl 6-(Bromomethyl)-4-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is a high-value brominated tetrahydropyrimidine derivative, serving as a critical synthetic intermediate in advanced organic synthesis. Its molecular architecture, featuring a reactive bromomethyl group and a versatile ester functionality, makes it indispensable for constructing complex heterocyclic scaffolds. This compound is primarily sought after by research institutions and pharmaceutical development teams for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of dihydropyrimidinone (DHPM) based drug candidates, which are explored for diverse therapeutic activities.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs targeting cancer, inflammation, and infectious diseases.
• Fine Chemical Synthesis: Serves as a precursor for creating complex molecules with potential applications in agrochemicals and specialty materials.
• Academic & R&D Laboratories: Employed in methodological development for novel C-C and C-N bond-forming reactions and heterocyclic chemistry research.

Basic Information

Product Name	Ethyl 6-(Bromomethyl)-4-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
CAS No.	14757-98-3
Molecular Formula	C9H13BrN2O3
Molecular Weight	277.12 g/mol
Synonyms	Ethyl 6-(bromomethyl)-4-methyl-2-oxo-3,4-dihydropyrimidine-5-carboxylate; 5-Carbethoxy-6-(bromomethyl)-4-methyl-3,4-dihydro-2(1H)-pyrimidinone; 6-(Bromomethyl)-4-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl ester; Ethyl 6-(bromomethyl)-4-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 5-Ethoxycarbonyl-6-(bromomethyl)-4-methyl-3,4-dihydropyrimidin-2(1H)-one; DHPM bromide derivative
EINECS	Contact for details

Quality Control

Our Ethyl 6-(Bromomethyl)-4-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.