Description

n-Epsilon Phospholysine is a chemically modified amino acid derivative where a phosphoryl group is attached to the ε-amino group of lysine. This compound is a crucial biochemical tool for studying protein phosphorylation, signal transduction pathways, and enzyme kinetics. It is primarily utilized by researchers and manufacturers in the fields of biochemistry, proteomics, and pharmaceutical development for creating phosphopeptide standards, enzyme substrates, and investigating post-translational modifications.

Application

• Biochemical Research: Used as a standard or substrate in enzymatic studies related to kinases, phosphatases, and other phospho-regulatory proteins.
• Proteomics & Mass Spectrometry: Serves as a critical reference compound for the identification and quantification of phosphopeptides in complex biological samples.
• Pharmaceutical Development: Employed in the design and screening of drugs that target phosphorylation-dependent disease mechanisms.
• Diagnostic Reagent Manufacturing: Incorporated into kits and assays for detecting phosphorylation events or specific enzyme activities.
• Enzyme Characterization: Acts as a specific substrate to determine the activity, specificity, and inhibition constants of phosphotransferase enzymes.
• Academic Research: Fundamental tool for university and institutional labs studying cell signaling, metabolism, and molecular biology.

Basic Information

Product Name	n-Epsilon Phospholysine
CAS No.	14721-74-5
Molecular Formula	C6H15N2O5P
Molecular Weight	226.17 g/mol
Synonyms	Nε-Phospho-L-lysine; L-Lysine, N6-(dihydrogen phosphate); Phospholysine; ε-Phosphoryl-L-lysine; N6-Phosphono-L-lysine; (2S)-2-Amino-6-(phosphonoamino)hexanoic acid; O-Phosphohomoserine (archaic/related); Lysine phosphate derivative
EINECS	Contact for details

Quality Control

Our n-Epsilon Phospholysine is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions or under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.