Description

H-Leu-Asn-Oh is a high-purity dipeptide building block, specifically the C-terminal carboxylic acid derivative of the Leu-Asn sequence. This compound is essential for advanced peptide synthesis and research, offering precise structural control for developing novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic institutions focused on peptide-based drug discovery and biochemical studies.

Application

• Pharmaceutical Intermediate: A key building block in the solid-phase and solution-phase synthesis of complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a standard or substrate in enzymatic studies, metabolic pathway investigations, and protein-protein interaction research.
• Cosmeceutical Development: Incorporated into the research and formulation of advanced skincare peptides aimed at anti-aging or skin barrier repair.
• Nutraceutical Ingredient Synthesis: Serves as a precursor in the development of specialized bioactive peptide supplements.
• Chemical Biology Probes: Utilized to create labeled or modified peptide fragments for diagnostic assays and cellular imaging studies.
• Academic & Industrial R&D: A fundamental reagent for method development in organic synthesis and peptide chemistry laboratories worldwide.

Basic Information

Product Name	H-Leu-Asn-Oh
CAS No.	14608-81-2
Molecular Formula	C10H19N3O4
Molecular Weight	245.28 g/mol
Synonyms	L-Leucyl-L-asparagine; Leu-Asn; L-Leu-L-Asn-OH; H-Leu-Asn-OH; N-(L-Leucyl)-L-asparagine; Leucyl-asparagine; Asparagine, N-L-leucyl-; (2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-3-carbamoylpropanoic acid
EINECS	Contact for details

Quality Control

Our H-Leu-Asn-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric purity, and identity confirmation by IR and MS. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm
Solubility	Soluble in water, DMSO; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.