Description

H-Met-Asp-Oh CAS NO 14595-65-4 is a high-purity, protected dipeptide building block, specifically L-Methionyl-L-aspartic acid. This compound is a critical intermediate for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics, offering precise control over amino acid sequence and side-chain functionality. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel therapeutic peptides targeting metabolic disorders, oncology, and cardiovascular diseases.
• Bioconjugation & Linker Chemistry: Used in the preparation of peptide-drug conjugates (PDCs) and antibody-drug conjugates (ADCs) due to its reactive carboxyl and amino termini.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and as a standard in analytical method development for peptide analysis.
• Cosmeceutical Peptides: A potential raw material in the synthesis of bioactive peptides for advanced skincare formulations.
• Food Science: Investigated for the development of bioactive peptides with potential nutritional or functional food applications.
• Material Science: A monomer for creating specialized peptide-based polymers and biomaterials with tailored properties.

Basic Information

Product Name	H-Met-Asp-Oh
CAS No.	14595-65-4
Molecular Formula	C9H16N2O5S
Molecular Weight	264.30 g/mol
Synonyms	L-Methionyl-L-aspartic acid; Methionine-Aspartic Acid; H-Met-Asp-OH; Met-Asp; L-Met-L-Asp; Aspartic acid, N-L-methionyl-; N-(N-L-Methionyl)-L-aspartic acid; NSC 334916
EINECS	Contact for details

Quality Control

Our H-Met-Asp-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via mass spectrometry (MS) and infrared spectroscopy (IR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-L isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.