Description

4-Methylglutamic Acid is a specialized non-proteinogenic amino acid derivative with the CAS registry number 14561-55-8. This compound serves as a valuable chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex molecules, active pharmaceutical ingredients (APIs), and novel biochemical probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a precursor or analog in metabolic pathway studies, enzyme inhibition assays, and the synthesis of specialized amino acid derivatives.
• Peptide Synthesis: Incorporated into custom peptides and peptidomimetics to modify structure, function, and stability for research applications.
• Agrochemical Development: Serves as a building block in the synthesis of advanced crop protection agents and herbicides.
• Fine Chemical Synthesis: Employed as a versatile intermediate in the multi-step synthesis of complex organic compounds for various high-value applications.
• Asymmetric Catalysis: Can be used to derive chiral ligands or auxiliaries for stereoselective synthesis.

Basic Information

Product Name	4-Methylglutamic Acid
CAS No.	14561-55-8
Molecular Formula	C6H11NO4
Molecular Weight	161.16 g/mol
Synonyms	(2S)-2-Amino-4-methylpentanedioic acid; L-4-Methylglutamic acid; (S)-4-Methylglutamic acid; 4-Methyl-L-glutamic acid; 2-Amino-4-methylglutaric acid; 4-Methylglutamate; 4-MGA
EINECS	Contact for details

Quality Control

Our 4-Methylglutamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (HPLC), chiral purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.