Description

H-Met-Met-Met-Oh is a tripeptide derivative composed of three methionine residues, a structure of significant interest in biochemical research and peptide synthesis. This compound matters for its role as a key intermediate and building block in the development of more complex peptides and peptidomimetics, where its unique sulfur-containing side chains can influence folding and reactivity. It is needed by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in drug discovery, proteomics, and as a standard for analytical method development.

Application

• Pharmaceutical Research: Serves as a crucial intermediate in the solid-phase and solution-phase synthesis of therapeutic peptides and peptide-based drug candidates.
• Biochemical Studies: Used as a model compound to study the properties, stability, and oxidation behavior of methionine-rich peptide sequences.
• Proteomics & Diagnostics: Can be utilized as a reference standard or calibrant in mass spectrometry and chromatographic analysis of peptides.
• Enzyme Substrate Studies: Acts as a potential substrate for investigating the activity of proteolytic enzymes and peptidases.
• Nutritional Science Research: Investigated for its role as a source of sulfur-containing amino acids in specialized nutritional formulations.
• Cosmetic Peptide Development: Explored as a component in the design of bioactive peptides for cosmetic and dermatological applications.

Basic Information

Product Name	H-Met-Met-Met-Oh
CAS No.	14486-15-8
Molecular Formula	C15H27N3O5S3
Molecular Weight	441.59 g/mol
Synonyms	Methionylmethionylmethionine; L-Methionyl-L-methionyl-L-methionine; H-Met-Met-Met-OH; Tri-L-methionine; Methionine Tripeptide; N-(Methionyl)-L-methionyl-L-methionine; (2S)-2-[[(2S)-2-[[(2S)-2-Amino-4-methylsulfanylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-methylsulfanylbutanoic acid
EINECS	Contact for details

Quality Control

Our H-Met-Met-Met-Oh is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere to prevent oxidation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.