Description

H-Met-Gly-Gly-Oh CAS NO 14486-02-3 is a high-purity tripeptide derivative, specifically the C-terminal carboxylic acid form of the sequence Methionyl-Glycyl-Glycine. This compound serves as a critical building block and intermediate in advanced organic synthesis and peptide research. It is primarily utilized by pharmaceutical R&D teams, biotech companies, and fine chemical manufacturers for developing novel therapeutic peptides and biochemical tools.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of longer, biologically active peptide sequences and peptidomimetics.
• Biochemical Research: Used as a substrate or standard in enzymatic studies and metabolic pathway investigations.
• Proteomics & Peptide Synthesis: Essential raw material in solid-phase and solution-phase peptide synthesis (SPPS) for research-scale production.
• Cosmetic Peptide Development: Potential intermediate in the formulation of bioactive peptides for advanced skincare applications.
• Academic Research: Serves as a model compound for studying peptide chemistry, stability, and purification techniques.
• Reference Standard: Used as a high-purity calibrant in analytical methods like HPLC and LC-MS for quality control in peptide manufacturing.

Basic Information

Product Name	H-Met-Gly-Gly-Oh
CAS No.	14486-02-3
Molecular Formula	C9H16N3O4S
Molecular Weight	262.30 g/mol
Synonyms	Methionylglycylglycine; L-Methionylglycylglycine; H-Met-Gly-Gly-OH; MGGF; Met-Gly-Gly; Glycylglycine, N-L-methionyl-; N-[(Methoxycarbonyl)methyl]-L-methionylglycine (related form); L-Methionine-Glycine-Glycine
EINECS	Contact for details

Quality Control

Our H-Met-Gly-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC for purity, chiral analysis, and identity confirmation to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are available upon request, providing full traceability and compliance documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions or under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	-30° to -40° (c=1 in water)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.