Description

Z-Pro-Leu-Gly-Nh2 is a synthetic tripeptide derivative, specifically a protected peptide sequence. This compound serves as a crucial building block (amino acid derivative) and intermediate in advanced organic synthesis and peptide research. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of more complex peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or standard in enzymatic studies, protease research, and metabolic pathway investigations.
• Peptide Library Synthesis: An essential component in combinatorial chemistry for creating diverse peptide libraries for drug discovery screening.
• Protease Inhibitor Development: Serves as a core structure or precursor in the design and development of specific protease inhibitors.
• Academic Research: Employed in university and institutional labs for studying peptide structure-activity relationships (SAR) and chemical biology.
• Custom Peptide Synthesis: A starting material for contract research and manufacturing organizations (CRMOs) offering bespoke peptide synthesis services.

Basic Information

Product Name	Z-Pro-Leu-Gly-Nh2
CAS No.	14485-80-4
Molecular Formula	C₂₂H₃₂N₄O₆
Molecular Weight	448.52 g/mol
Synonyms	Z-Pro-Leu-Glycinamide; Benzyloxycarbonyl-Prolyl-Leucyl-Glycinamide; CBZ-Pro-Leu-Gly-NH₂; N-Carbobenzoxy-L-prolyl-L-leucyl-glycinamide; Z-L-Pro-L-Leu-Gly-NH₂; L-Proline, N-[(phenylmethoxy)carbonyl]-, (2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-; Pro-Leu-Gly-NH₂, Nα-Z-; Z-Pro-Leu-Gly Amide
EINECS	Contact for details

Quality Control

Our Z-Pro-Leu-Gly-Nh2 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.