Description

Cyclo(Ala-Phe) is a synthetic cyclic dipeptide, also known as a diketopiperazine (DKP), formed from the amino acids alanine and phenylalanine. This compound serves as a crucial pharmacophore and structural motif in medicinal chemistry and biochemical research. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors for developing novel therapeutic agents and studying peptide interactions.

Application

• Pharmaceutical Intermediate: Used as a core scaffold or building block in the research and development of new drug candidates, particularly for its conformational constraints.
• Biochemical Research: Serves as a model compound for studying peptide stability, cyclization reactions, and enzyme-substrate interactions.
• Protease Inhibitor Studies: Investigated for its potential as a protease inhibitor due to its stable cyclic structure mimicking peptide bonds.
• Fine Chemical Synthesis: Employed in the synthesis of more complex peptidomimetics and macrocyclic compounds.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Cyclo(Ala-Phe)
CAS No.	14474-78-3
Molecular Formula	C12H14N2O2
Molecular Weight	218.25 g/mol
Synonyms	Cyclo(L-alanyl-L-phenylalanine); 3-Benzyl-6-methylpiperazine-2,5-dione; Cyclo(alanine-phenylalanine); L-Ala-L-Phe diketopiperazine; DKP-Ala-Phe; 2,5-Piperazinedione, 3-benzyl-6-methyl-; (3S,6S)-3-Benzyl-6-methylpiperazine-2,5-dione
EINECS	Contact for details

Quality Control

Our Cyclo(Ala-Phe) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.