Description

4-Amino-2-Chloro-5-Methylpyrimidine is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both amino and chloro substituents, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a fundamental building block in medicinal chemistry for creating novel heterocyclic libraries and exploring structure-activity relationships.
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized dyes and functional colorants.
• Material Science: Investigated for use in the development of organic electronic materials and ligands for metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Amino-2-Chloro-5-Methylpyrimidine
CAS No.	14394-70-8
Molecular Formula	C5H6ClN3
Molecular Weight	143.57 g/mol
Synonyms	2-Chloro-5-methyl-4-pyrimidinamine; 5-Methyl-2-chloro-4-aminopyrimidine; 2-Chloro-4-amino-5-methylpyrimidine; 4-Amino-2-chloro-5-methyl-pyrimidine; 4-Pyrimidinamine, 2-chloro-5-methyl-; ACMC-1C7V1; SCHEMBL118204; CTK8G0135
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Chloro-5-Methylpyrimidine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.