Description

Glycyl-Glycyl-Proline is a synthetic tripeptide derivative of the Gly-Pro dipeptide sequence, known for its role as a substrate and inhibitor in enzymatic studies. This compound is valued for its high purity and specificity in biochemical and pharmaceutical research applications. It is primarily utilized by research institutions and manufacturers in the life sciences sector for investigating collagen metabolism, enzyme kinetics, and as a building block in peptide synthesis.

Application

• Biochemical Research: Used as a specific substrate for studying prolyl oligopeptidase (POP) and other proline-specific enzymes.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the development of peptide-based therapeutics and diagnostic agents.
• Enzyme Inhibition Studies: Employed to investigate enzyme inhibition mechanisms relevant to neurological and fibrotic disorders.
• Collagen Metabolism Research: Acts as a model compound for researching collagen degradation and turnover pathways.
• Peptide Synthesis: Functions as a protected tripeptide building block for the solid-phase or solution-phase synthesis of larger, more complex peptides.
• Academic & Industrial R&D: Essential for basic and applied research in biochemistry, molecular biology, and medicinal chemistry laboratories worldwide.

Basic Information

Product Name	Glycyl-Glycyl-Proline
CAS No.	14379-76-1
Molecular Formula	C10H16N4O4
Molecular Weight	256.26 g/mol
Synonyms	Gly-Gly-Pro; GGP; H-Gly-Gly-Pro-OH; Glycyl-glycyl-L-proline; L-Proline, glycylglycyl-; Glycylglycylproline; Tripeptide GGP; 2-[[2-[(2S)-pyrrolidine-2-carbonyl]amino]acetyl]aminoacetic acid
EINECS	Contact for details

Quality Control

Our Glycyl-Glycyl-Proline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, MS). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.