Description

D-Mannosamine is a vital amino sugar derivative, serving as a key chiral building block and biochemical precursor in advanced synthesis. Its significance lies in its role as an intermediate for the production of sialic acid analogs and other glycosylated compounds with biological activity. This high-purity material is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors, particularly for developing novel therapeutics, diagnostic tools, and glycobiology research.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of sialic acid derivatives (e.g., N-acetylneuraminic acid) used in antiviral and anticancer drug development.
• Glycobiology Research: Fundamental building block for studying carbohydrate-protein interactions, cell signaling, and glycosylation pathways.
• Bioconjugate Chemistry: Used in the preparation of glycoconjugates, glycoproteins, and labeled probes for diagnostic and imaging applications.
• Enzyme Substrate & Inhibitor Synthesis: Serves as a core structure for developing specific inhibitors or substrates for glycosidases and glycosyltransferases.
• Nutritional & Cosmetic Science: Investigated for potential applications in nutraceuticals and advanced cosmetic formulations targeting skin glycation.
• Chemical Biology Tool Development: Employed in the synthesis of metabolic probes for tracking cellular uptake and metabolism of amino sugars.

Basic Information

Product Name	D-Mannosamine
CAS No.	14307-02-9
Molecular Formula	C6H13NO5
Molecular Weight	179.17 g/mol
Synonyms	2-Amino-2-deoxy-D-mannose; D-Mannose, 2-amino-2-deoxy-; Mannosamine; 2-Amino-2-deoxymannose; D-(-)-Mannosamine; 2-Amino-2-deoxy-D-glucose (stereoisomer); 14307-02-9; D-Mannosamine hydrochloride (salt form)
EINECS	238-248-9

Quality Control

Our D-Mannosamine is produced under a stringent quality management system. Each batch is tested to meet exacting specifications for identity, purity, and impurity profiles, ensuring consistency for critical research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing results for assay, chiral purity, related substances, residual solvents, and microbiological tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	-2.5° to -3.5° (c=1 in H2O)
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.