Description

5-Bromo-1-Methylpyrimidin-2-One is a halogenated pyrimidinone derivative, a versatile and high-value organic building block. Its core value lies in its reactive bromine substituent, which enables efficient cross-coupling and functionalization reactions in complex organic synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for biological activity.
• Organic Synthesis Building Block: The bromine atom facilitates key reactions like Suzuki, Stille, and Buchwald-Hartwig couplings for constructing complex molecular architectures.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Employed as a scaffold or labeling reagent in the design of molecular probes and enzyme inhibitors.

Basic Information

Product Name	5-Bromo-1-Methylpyrimidin-2-One
CAS No.	14248-01-2
Molecular Formula	C5H5BrN2O
Molecular Weight	189.01 g/mol
Synonyms	5-Bromo-1-methyl-1H-pyrimidin-2-one; 5-Bromo-1-methylpyrimidin-2(1H)-one; 1-Methyl-5-bromopyrimidin-2(1H)-one; 2(1H)-Pyrimidinone, 5-bromo-1-methyl-; 5-Bromo-1-methyl-2-pyrimidinone; 5-Bromo-1-methyl-2(1H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-Methylpyrimidin-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.