Description

n-Octadecanoyl-L-Alanine is a high-purity, synthetic amino acid derivative where the stearic acid (C18) moiety is conjugated to the L-isomer of alanine. This molecular design combines the lipophilic character of a long alkyl chain with the chiral, functional backbone of a natural amino acid, making it a valuable building block for advanced material science and life science applications. It is particularly sought after by researchers and manufacturers in the pharmaceutical, cosmetic, and specialty chemical sectors for its role in synthesizing peptide-mimetics, surfactants, and self-assembling materials. The compound, identified by CAS NO 14246-60-7, is supplied under stringent quality control to ensure batch-to-batch consistency for critical R&D and production processes.

Application

• Pharmaceutical Intermediates: Serves as a key chiral synthon for the development of novel peptide-based drugs and prodrugs to enhance bioavailability.
• Cosmetic Actives & Surfactants: Used in the formulation of high-end skincare products as a biocompatible emulsifier or a lipophilic moiety in amino acid-based surfactants for mild cleansing.
• Bioconjugation & Linker Chemistry: Employed in the synthesis of lipid-peptide conjugates for drug delivery systems, diagnostic probes, and biomaterial surface functionalization.
• Supramolecular Chemistry: Acts as a precursor for gelators and building blocks in the design of self-assembled nanostructures and hydrogels.
• Biochemical Research: Utilized as a substrate or inhibitor in enzymatic studies and metabolic pathway research due to its specific stereochemistry.
• Specialty Polymer Additives: Incorporated into polymers to modify surface properties, impart chirality, or introduce biodegradable segments.

Basic Information

Product Name	n-Octadecanoyl-L-Alanine
CAS No.	14246-60-7
Molecular Formula	C21H41NO3
Molecular Weight	355.56 g/mol
Synonyms	L-Alanine, N-(1-oxooctadecyl)-; Stearoyl-L-alanine; N-Stearoyl-L-alanine; N-Octadecanoyl-L-alanine; (2S)-2-(Octadecanoylamino)propanoic acid; Alanine, N-stearoyl-, L-; N-(1-Oxooctadecyl)-L-alanine
EINECS	238-149-8

Quality Control

Our n-Octadecanoyl-L-Alanine is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the high standards required for research and industrial use. Each batch is controlled for identity, purity, and chiral integrity using techniques such as HPLC, NMR, and optical rotation. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	+15.0° to +20.0° (c=1 in CHCl3)
Melting Point	95°C - 105°C
Loss on Drying	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.