Description

n-(Hydroxyacetyl)-2-o-Methyl-α-Neuraminic Acid is a chemically modified derivative of neuraminic acid, a key sialic acid building block. This compound is a crucial intermediate in the synthesis of more complex sialylated glycoconjugates and glycomimetics, enabling precise biochemical research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the fields of glycobiology, antiviral drug discovery, and advanced diagnostic reagent production.

Application

• Glycobiology Research: A vital intermediate for the chemical and enzymatic synthesis of sialylated oligosaccharides and glycoproteins to study cell-cell interactions and signaling.
• Antiviral Agent Development: Serves as a precursor in creating neuraminidase inhibitors and other compounds targeting viral adhesion and entry mechanisms.
• Diagnostic Reagent Synthesis: Used in the production of labeled probes and standards for detecting sialic acid-related enzymes or biomarkers in clinical assays.
• Pharmaceutical Intermediates: Acts as a key building block for the development of novel therapeutic agents, including anti-inflammatory and anti-metastatic drugs.
• Bioconjugation and Probe Design: Facilitates the creation of bioconjugates for targeted drug delivery systems and imaging agents due to its modifiable functional groups.

Basic Information

Product Name	n-(Hydroxyacetyl)-2-o-Methyl-α-Neuraminic Acid
CAS No.	14206-42-9
Molecular Formula	C13H21NO10
Molecular Weight	351.31 g/mol
Synonyms	5-Acetamido-2,6-anhydro-3,5-dideoxy-D-glycero-D-galacto-non-2-enonic Acid, 9-Hydroxy-4,7,8,9-tetradeoxy Derivative; 2-O-Methyl-N-acetylneuraminic Acid Hydroxyacetyl Derivative; N-Glycolyl-2-O-methylneuraminic Acid; Sialic Acid Derivative; Neu5Gc2Me; N-(Hydroxyacetyl)-2-O-methylneuraminic Acid
EINECS	Contact for details

Quality Control

Our n-(Hydroxyacetyl)-2-o-Methyl-α-Neuraminic Acid is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.