Description

2-Acetamido-2-Deoxy-1,3,4,6-Tetra-0-Acetyl-α-D-Glucopyranose is a key acetylated derivative of N-acetylglucosamine, serving as a vital protected intermediate in sophisticated organic synthesis. Its value lies in providing a stable, reactive scaffold for the controlled construction of complex carbohydrate molecules and glycoconjugates. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors, particularly for developing novel glycotherapeutics, diagnostic probes, and advanced biomaterials.

Application

• Glycochemistry & Glycobiology Research: A fundamental protected intermediate for the chemical and enzymatic synthesis of complex oligosaccharides, glycopeptides, and glycolipids.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs targeting carbohydrate-mediated biological processes.
• Bioconjugate Development: Serves as a precursor for creating labeled sugars, affinity tags, and other tools for studying protein-carbohydrate interactions.
• Chiral Building Block: Utilized in asymmetric synthesis to introduce stereochemical complexity due to its well-defined α-D-gluco configuration.
• Material Science: A starting material for synthesizing functionalized polymers and hydrogels with bioactive carbohydrate motifs.
• Reference Standard: Employed as a high-purity analytical standard in quality control and method development for carbohydrate analysis.

Basic Information

Product Name	2-Acetamido-2-Deoxy-1,3,4,6-Tetra-0-Acetyl-α-D-Glucopyranose
CAS No.	14086-90-9
Molecular Formula	C16H23NO10
Molecular Weight	389.36 g/mol
Synonyms	1,3,4,6-Tetra-O-acetyl-2-acetamido-2-deoxy-α-D-glucopyranose; N-Acetylglucosamine Tetraacetate (α-form); GlcNAc Tetraacetate (α-anomer); 2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-α-D-glucopyranose; α-D-Glucopyranose, 2-acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-; NAG Tetraacetate (α-D-); Peracetylated N-Acetyl-α-D-glucosamine; Ac4GlcNAc-α
EINECS	Contact for details

Quality Control

Our 2-Acetamido-2-Deoxy-1,3,4,6-Tetra-0-Acetyl-α-D-Glucopyranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]20/D	+40.0° to +44.0° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.