Description

2-Cyanopyrimidine is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its bifunctional structure, featuring both a pyrimidine ring and a reactive nitrile group, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for research and production in the pharmaceutical, agrochemical, and material science industries, where it serves as a precursor to various active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the pyrimidine core's bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysts for cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized to develop molecular probes and labeled compounds for biochemical and diagnostic research.
• Custom Synthesis and R&D: A fundamental starting material for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	2-Cyanopyrimidine
CAS No.	14080-23-0
Molecular Formula	C5H3N3
Molecular Weight	105.10 g/mol
Synonyms	Pyrimidine-2-carbonitrile; 2-Pyrimidinecarbonitrile; 2-Pyrimidyl cyanide; Cyanopyrimidine; 2-Cyano-pyrimidine; α-Cyanopyrimidine
EINECS	237-896-5

Quality Control

Our 2-Cyanopyrimidine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.