Description

Z-Pro-Ala-Oh is a protected dipeptide building block widely used in solid-phase peptide synthesis (SPPS). This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise stereochemistry. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for developing therapeutic peptides, biochemical probes, and novel biomaterials.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential assembly of custom peptide chains.
• Pharmaceutical Research: Building block for the development of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation: Used in the synthesis of peptide tags, linkers, and carriers for drug delivery systems.
• Enzyme Substrate Studies: Serves as a substrate or inhibitor analog in protease and peptidase research.
• Chemical Biology: Fundamental component for creating peptide libraries and probes to study protein-protein interactions.
• Academic & Industrial R&D: Critical raw material for exploratory chemistry and process development in peptide science.

Basic Information

Product Name	Z-Pro-Ala-Oh
CAS No.	14030-00-3
Molecular Formula	C16H20N2O5
Molecular Weight	320.34 g/mol
Synonyms	Z-Pro-Ala-OH; N-Cbz-L-Prolyl-L-Alanine; N-Carbobenzoxy-L-prolyl-L-alanine; Cbz-L-Pro-L-Ala-OH; Nα-Carbobenzyloxy-L-prolyl-L-alanine; Benzyloxycarbonyl-L-prolyl-L-alanine; (S)-2-(((Benzyloxy)carbonyl)amino)-1-((S)-pyrrolidine-2-carboxamido)propanoic acid; Z-L-Pro-L-Ala-OH
EINECS	Contact for details

Quality Control

Our Z-Pro-Ala-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.